产品货号：
Z19230
中文名称：
Lactadherin/MFGE8抗体
英文名称：
Anti-Lactadherin/MFGE8 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Lactadherin/MFGE8 Antibody |
| 指标别名 | BA46;Breast epithelial antigen BA46;EDIL1;HMFG;hP47;HsT19888;Lactadherin;MFG E8;MFGE8;MFG-E8;MFGM;Milk fat globule EGF factor 8;OAcGD3S;SED1;SPAG10 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ELISA |
| 基因名称 | MFGE8 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Milk Fat Globule 1/MFGE8 recombinant protein (Position:L24-C387). |
| 实际分子量 | 43KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | MFGE8(Milk Fat Globule-Egf Factor 8),also called as Lactadherin or SED1,is a protein which in humans is encoded by the MFGE8 gene.Mfge8 is secreted protein found in vertebrates,including mammals as well as birds.By fluorescence in situ hybridization,Collins et al.(1997) mapped the MFGE8 gene to chromosome 15q25.Hanayama et al.(2002) found that MFGE8 is a factor that links apoptotic cells to phagocytes.MFGE8 specifically bound to apoptotic cells by recognizing aminophospholipids such as phosphatidylserine.MFGE8,when engaged by phospholipids,bound to cells via its RGD motif.It bound particularly strongly to cells expressing alpha-V-beta-3 integrin.Bu et al.(2007) showed that Mfge8 was expressed in intestinal lamina propria macrophages in mice.Using a wound-healing assay,they showed that Mfge8 promoted migration of intestinal epithelial cells through a PKC-epsilon(PRKCE)-dependent mechanism. |
| Uniprot ID | Q08431 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P). |
| 基因名全称 | milk fat globule EGF and factor V/VIII domain containing |
| 蛋白名全称 | Lactadherin |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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